MOHS MICROGRAPHIC SURGERY FOR BASAL CELL CARCINOMA: A REVIEW OF TREATMENT RESULTS

Authors

  • Son Nguyen Hong National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Duc Le Van Hanoi Medical University
  • Giang Pham Ngan Hanoi Medical University
  • Binh Vu Nguyen National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Quan Nguyen Dinh National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Quang Nguyen Huu National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Tam Vu Dinh National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Tung Nguyen Canh National Hospital of Dermatology and Venereology, Hanoi, Vietnam
  • Hien Le Thi Thanh National Hospital of Dermatology and Venereology, Hanoi, Vietnam

DOI:

https://doi.org/10.56320/tcdlhvn.42.128

Keywords:

basal cell carcinoma, Mohs micrography surgery.

Abstract

Objectives: To evaluate the results of Mohs Micrography Surgery (MMS) in the treatment of basal cell carcinoma (BCC).

Materials and methods: We used the database of PUBMED and EMBASE to evaluate the results of MMS in treatment of BCC.

Results: Nine studies with the total number of 5845 BCC cases were included in this review, the follow-up time varied from 12 to 42 months. The overall cumulative probabilities of recurrence after MMS were 2.4%. The cumulative probability of recurrence for the primary BCC group and the recurrent BCC group was 2.9% and 7.2%, respectively. In the recurrent BCC group, the cumulative probability of recurrence after MMS was lower than after standard surgical excision (SSE) (3.9% vs 13.5%, p < 0.05). In MMS group, 52% of patients required one round of excision to achieve complete removal of BCC, 34% needed two rounds and 14% needed three rounds. The size of final skin defect after MMS was 1.34 times larger than that of the primary tumor (p < 0.05).

Conclusion: MMS is superior to SSE in BCC treatment, with lower recurrence rate and better normal skin-sparing. Therefore, MMS is strongly recommended for surgical treatment of BCC, especially in high-risk BCC.

Received 28 June 2023
Revised 26 September 2023
Accepted 29 November 2023

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Published

2024-01-21

How to Cite

Nguyen Hong, S., Le Van, D., Pham Ngan, G., Vu Nguyen, B., Nguyen Dinh, Q., Nguyen Huu, Q., Vu Dinh, T., Nguyen Canh, T., & Le Thi Thanh, H. (2024). MOHS MICROGRAPHIC SURGERY FOR BASAL CELL CARCINOMA: A REVIEW OF TREATMENT RESULTS. Vietnamese Journal of Dermatology and Venereology, (42). https://doi.org/10.56320/tcdlhvn.42.128

Issue

Section

SCIENTIFIC RESEARCH

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